Currently: Software Engineer at RNWBL
Hello! I am a Software Engineer working at RNWBL to help empower the future of renewable energy infrastructure. I graduated from from Washington University in St. Louis with a BS/MS in Computer Science with a Certificate in Engineering Management and a BS in Biochemistry from Kenyon College where I wrote my senior review capstone on computational photochemistry of vision.
BS/MS Computer Science - Washington University in St. Louis
Certificate in Engineering Management
Aug 2020 - Dec 2022
BS Biochemistry - Kenyon College
Aug 2016 - May 2020
Software Engineer
February 2023 - Present
BI Software Engineer Intern
July 2021 - December 2022
Senior Capstone - Advancing Computational Exploration into the Photochemistry of Vision - Kenyon College (PDF)
When light hits 11-cis-retinal (PSB11), the molecule becomes excited and isomerizes into the all-trans-retinal (PSBT), influenced by both electrostatic and steric effects. The photoisomerization reaction dynamics have been increasingly investigated with computational models like CASSCF, CASPT2, QM/MM, AMBER, and many more. This review examines methods proposed by recent computational and experimental investigations of opsin proteins that explore steric and electrostatic manipulations of RPSB and the binding pocket for advanced QM/MM simulations.
MERN Encrypted Messaging Application
Built an ecrpyted messaging application using the MERN (MongoDB, Express, React, Node.js) stack. Messages are encryped with AES256 before stored in the MongoDB, insuring user privacy.
Computational Chemistry Research - Dr. John Payton PhD
Investigated novel computational research into light-activated biomolecular systems with Visiting Professor Dr. John Payton Ph.D. During this research, I used quantum chemistry software packages like Avogadro, Gaussian, and OpenMolcas, and wrote Python scripts to organize my virtual working environment and rapidly submit calculations to the cloud.
Social Media Application
Built the front and back-end of a social media application that can store user information within SQL databases and use PHP to dynamically generate content.
Mount Vernon Archival Database (MVAD)
For a community outreach project, our team constructed an archival database to access old records that cannot be transferred to a new system and managed weekly meetings with clients.
CongressAPI
An application built on Flask and Django that visualizes funding information for congressional candidates running for re-election in the next term. Congress member data is collected using ProPublica and OpenSecrets APIs.
Prediction of Protein Complex Structure Using Surface-Induced Dissociation and Cryo-Electron Microscopy - May 2021
In a previous study, it was demonstrated that the scoring of structures generated from protein–protein docking could be improved with the inclusion of SID data; however, this work relied on knowledge of the correct tertiary structure and only built full complexes for a few cases. Here, we performed docking using input structures that require less prior knowledge, using homology models, unbound crystal structures, and bound+perturbed crystal structures. This lead to more accurately predicted tertiary structures.
Published in Analytical Chemistry
Kenyon Summer Science Scholars Rise Science Fellowship - April 2018
Designed to fund off-campus research opportunities for students who already have research experience. With support from the Sherman Fairchild Foundation, funds will be given to support student research at qualified universities and other research institutions.
Ohio State University Summer Undergraduate Research Experience (SURE) - March 2018
The Ohio State University's Department of Chemistry and Biochemistry, and the Five Colleges of Ohio, Inc. sponsored paid summer research internships in either chemistry or biochemistry from May through June of 2018. The 10-week program allowed students at The College of Wooster, Denison University, Kenyon College, Oberlin College, and Ohio Wesleyan University to work with Ohio State University faculty members.
Feel free to contact me at c.shane@wustl.edu for software development related employment inquries.